Medical and Health Sciences

Fish oil’s cancer-fighting reputation may hinge on a little-known gene. Researchers discovered that omega-3s like EPA and DHA help curb colorectal cancer only when the enzyme ALOX15 is present. Without it, fish oil sometimes increased tumor growth in mice—especially DHA. The results suggest that not all supplements work the same way, and genetics could determine who truly benefits.

Scientists at Cedars-Sinai have uncovered a surprising repair system in the spinal cord that could open new doors for treating paralysis, stroke, and diseases like multiple sclerosis. They found that special support cells called astrocytes—located far from the actual injury—spring into action after damage. These “lesion-remote astrocytes” send out a protein signal, CCN1, that reprograms immune cells to efficiently clean up fatty nerve debris.

Microplastics and nanoplastics are now found everywhere on Earth, from ocean depths to agricultural soils and even inside the human body. Yet scientists still struggle to understand what these particles actually do once they enter living organisms. A new study proposes an innovative fluorescence-based strategy that could allow researchers to track microplastics in real time as they move, transform, and degrade inside biological systems.

A low-fat vegan diet—without cutting calories or carbs—may help people with type 1 diabetes significantly reduce how much insulin they need, and how much they spend on it. In a new analysis published in BMC Nutrition, participants following the plant-based plan lowered their daily insulin use by 28%, while those on a portion-controlled diet saw no meaningful change.

A robotic arm that moves too quickly can feel creepy. One that moves too slowly feels awkward and unhelpful. In a VR study, researchers found that AI-powered prosthetic arms were best accepted when they moved at a natural, human-like speed—about one second per reach. That sweet spot boosted feelings of control, comfort, and even trust in the robot.

A protein called HIF1 may be the missing link behind painful tendon injuries like jumper’s knee and tennis elbow. Researchers showed that high levels of HIF1 actually cause harmful changes that make tendons brittle and prone to pain. In experiments, turning the protein off protected tendons — even under heavy strain.

A newly identified protein may hold the key to rejuvenating aging brain cells. Researchers found that boosting DMTF1 can restore the ability of neural stem cells to regenerate, even when age-related damage has set in. Without it, these cells struggle to renew and support memory and learning. The findings raise hopes for treatments that could slow or even reverse aspects of brain aging.

Swapping just an hour of TV a day for something more active could significantly lower the risk of developing major depression—especially in middle age. A large Dutch study tracking more than 65,000 adults over four years found that replacing 60 minutes of TV with other activities cut depression risk by 11% overall, and by nearly 19% in middle-aged adults. The more time people reallocated—up to two hours—the greater the benefit, with risk dropping as much as 43% in midlife.

A six-week study from the University of Nottingham suggests that pairing fermented kefir with a diverse prebiotic fiber mix may deliver a powerful anti-inflammatory boost. This “synbiotic” combination outperformed omega-3 supplements and fiber alone, leading to the broadest drop in inflammation-related proteins in healthy adults. By feeding beneficial microbes and helping them produce compounds like butyrate, the combo appeared to improve overall immune balance and metabolic health.

A simple brain-training program that sharpens how quickly older adults process visual information may have a surprisingly powerful long-term payoff. In a major 20-year study of adults 65 and older, those who completed five to six weeks of adaptive “speed of processing” training — along with a few booster sessions — were significantly less likely to develop dementia, including Alzheimer’s disease, even two decades later. Participants who received the boosted speed training had a 25% lower dementia risk compared to those who received no training, making it the only intervention in the trial to show such a lasting protective effect.

A new clinical trial suggests that changing when you eat could make a meaningful difference for people living with Crohn’s disease. Researchers found that time-restricted feeding, a form of intermittent fasting that limits meals to an 8-hour daily window, reduced disease activity by 40% and cut abdominal discomfort in half over 12 weeks. Participants also lost weight and showed healthier inflammation and immune markers, even though they did not reduce calories or change what they ate.

Three major reviews commissioned by the World Health Organization find that GLP-1 drugs including tirzepatide (sold as Mounjaro and Zepbound), semaglutide (Ozempic and Wegovy), and liraglutide (Victoza and Saxenda) can lead to substantial weight loss in people with obesity. But while the results are impressive, researchers caution that most trials were funded by drugmakers, long term safety data are still limited, and side effects such as nausea are common.

Depression in older adults may sometimes signal the early stages of Parkinson’s disease or Lewy body dementia. Researchers found that depression often appears years before diagnosis and remains elevated long afterward, unlike in other chronic illnesses. This suggests depression may reflect early brain changes rather than emotional distress alone.

A cooler bedroom might be better for older sleepers than previously thought. Researchers found that keeping nighttime temperatures at 75°F reduced stress responses and helped the heart work more efficiently during sleep. Hot nights usually force the heart to work harder, interfering with recovery. As climate change drives warmer nights, this small adjustment could make a big difference.

Blood vessels twist, branch, narrow, and balloon in ways that dramatically affect how blood flows — but most lab models have long treated them like straight pipes. Researchers at Texas A&M have now built a new kind of “vessel-chip” that mirrors the real complexity of human blood vessels, from aneurysms to dangerous constrictions.

Why does the same virus barely faze one person while sending another to the hospital? New research shows the answer lies in a molecular record etched into our immune cells by both our genes and our life experiences. Scientists at the Salk Institute have created a detailed epigenetic map of human immune cells, revealing how inherited traits and past exposures—like infections, vaccines, or even environmental chemicals—shape immune responses in different ways.

A bonobo named Kanzi surprised scientists by successfully playing along in pretend tea party experiments, tracking imaginary juice and grapes as if they were real. He consistently pointed to the correct locations of pretend items, while still choosing real food when given the option. The results suggest that imagination may not be exclusive to humans after all.

Ultra-processed foods are everywhere in the American diet, and researchers are finding alarming consequences. Using national health data, scientists found that adults with the highest intake of these foods had a 47% higher risk of heart attack or stroke. The results held even after accounting for age, smoking, and income. Experts say reducing ultra-processed foods could become as important to public health as cutting back on tobacco once was.

Scientists have uncovered a surprising way tumors turn the immune system to their advantage. Researchers at the University of Geneva found that neutrophils—normally frontline defenders against infection—can be reprogrammed inside tumors to fuel cancer growth instead. Once exposed to the tumor environment, these immune cells begin producing a molecule called CCL3 that actively promotes tumor progression.

Human evolution has long been tied to growing brain size, and new research suggests prenatal hormones may have played a surprising role. By studying the relative lengths of index and ring fingers — a clue to oestrogen and testosterone exposure in the womb — researchers found that higher prenatal estrogen was linked to larger head size in newborn boys.

Autism has long been thought of as a condition that mostly affects boys, but a massive study from Sweden suggests that idea may be misleading. Tracking nearly 3 million people over decades, researchers found that while boys are diagnosed more often in childhood, girls steadily catch up during their teenage years. By early adulthood, autism diagnoses among males and females are nearly equal.

A large U.S. study suggests that not getting enough lycopene—the antioxidant that gives tomatoes their red color—may seriously raise the risk of severe gum disease in older adults. Researchers found that seniors with adequate lycopene intake had about one-third the risk of severe periodontitis compared with those who fell short.

A sweeping new review of ADHD treatments—drawing on more than 200 meta-analyses—cuts through years of mixed messaging and hype. To make sense of it all, researchers have launched an interactive, public website that lets people with ADHD and clinicians explore what actually works, helping them make clearer, evidence-based decisions—while also highlighting a major gap: most solid evidence only covers short-term effects, even though long-term treatment is common.

Researchers at the University of Michigan have created an AI system that can interpret brain MRI scans in just seconds, accurately identifying a wide range of neurological conditions and determining which cases need urgent care. Trained on hundreds of thousands of real-world scans along with patient histories, the model achieved accuracy as high as 97.5% and outperformed other advanced AI tools.

We don’t experience the world through neat, separate senses—everything blends together. Smell, touch, sound, sight, and balance constantly influence one another, shaping how food tastes, objects feel, and even how heavy our bodies seem. Scientists now believe humans may have more than 20 distinct senses working at once. Everyday illusions and experiences reveal just how surprisingly complex perception really is.

Scientists have discovered that DNA behaves in a surprising way when squeezed through tiny nanopores, overturning a long-held assumption in genetics research. What researchers once thought were knots causing messy electrical signals turn out to be something else entirely: twisted coils called plectonemes, formed as flowing ions inside the pore spin the DNA like a phone cord. These twists can linger and grow as DNA moves through, leaving clear electrical fingerprints.

A long-term study found that women who closely followed a Mediterranean diet had a much lower risk of stroke. The strongest benefits were seen in women who ate more plant-based foods, fish, and olive oil while cutting back on red meat and saturated fats. Their risk dropped across all major stroke types, including bleeding strokes, which are less commonly studied. The findings suggest diet may be a powerful but overlooked factor in stroke prevention.

Scientists have discovered why ovarian cancer spreads so rapidly through the abdomen. Cancer cells enlist normally protective abdominal cells, forming mixed groups that work together to invade new tissue. These helper cells lead the way, allowing cancer to spread faster and resist chemotherapy. The findings uncover a critical weakness that future treatments may target.

A long-term study of older adults with moderate hearing loss found that hearing aids did not lead to better performance on memory or thinking tests, but the story did not end there. Over seven years, people who were prescribed hearing aids were significantly less likely to develop dementia than those who were not.

A centuries-old Chinese medicinal root is getting new scientific attention as a potential game-changer for common hair loss. Polygonum multiflorum, long believed to restore dark, healthy hair, appears to work on multiple fronts at once—blocking hair-shrinking hormones, protecting follicles from damage, activating natural regrowth signals, and boosting blood flow to the scalp.

A new international study points to a specific brain network as the core driver of Parkinson’s disease. Scientists found that this network becomes overly connected, disrupting not just movement but also thinking and other bodily functions. When researchers targeted it with non-invasive brain stimulation, patients showed much stronger symptom improvement than with conventional stimulation. The discovery could reshape how Parkinson’s is diagnosed and treated.

Your gut is home to trillions of bacteria that constantly “sense” their surroundings to survive and thrive. New research shows that beneficial gut microbes, especially common Clostridia bacteria, can detect a surprisingly wide range of chemical signals produced during digestion, including byproducts of fats, proteins, sugars, and even DNA. These microbes use specialized sensors to move toward valuable nutrients, with lactate and formate standing out as especially important fuel sources.

Researchers have found a surprising way to turn sunflower oil waste into a powerful bread upgrade. By replacing part of wheat flour with partially defatted sunflower seed flour, breads became dramatically richer in protein, fiber, and antioxidants—while also offering potential benefits for blood sugar and fat digestion.

Scientists have uncovered promising clues that compounds found in Aloe vera could play a role in fighting Alzheimer’s disease. Using advanced computer modeling, researchers discovered that beta-sitosterol—a natural plant compound—strongly interacts with two key enzymes involved in memory loss and cognitive decline. The compound showed stability, strong binding, and favorable safety indicators, making it a standout candidate for future drug development.

Scientists have identified a promising new compound, Mic-628, that can reliably shift the body’s internal clock forward—something that’s notoriously hard to do. By targeting a key clock-control protein, Mic-628 jump-starts the gene that sets daily rhythms, synchronizing both the brain’s master clock and clocks throughout the body. In mice experiencing simulated jet lag, a single dose cut recovery time nearly in half.

What a mother eats during pregnancy may quietly shape her child’s liver health years down the road—but new research suggests there may be a way to tip the odds back in a healthier direction. Scientists found that a natural compound made by healthy gut bacteria dramatically reduced fatty liver disease in the offspring of mice whose mothers ate a high-fat, high-sugar diet. The compound, called indole, appeared to protect the liver, improve blood sugar, limit weight gain, and even reshape the gut microbiome in lasting ways.

New research suggests the astringent sensation caused by flavanols could act as a direct signal to the brain, triggering effects similar to a mild workout for the nervous system. In mouse experiments, flavanol intake boosted activity, curiosity, learning, and memory—despite these compounds barely entering the bloodstream. The key appears to be sensory stimulation: the taste itself activates brain pathways linked to attention, motivation, and stress response, lighting up regions involved in arousal and memory.

New simulations reveal that both H1N1 and COVID-19 spread across U.S. cities in a matter of weeks, often before officials realized what was happening. Major travel hubs helped drive rapid nationwide transmission, with air travel playing a bigger role than daily commuting. Unpredictable transmission patterns made real-time forecasting especially difficult. The study highlights why early detection systems are critical for slowing future pandemics.

A major study suggests menopause is linked to changes in brain structure, mental health, and sleep. Brain scans revealed grey matter loss in areas tied to memory and emotional regulation, while many women reported increased anxiety, depression, and fatigue. Hormone therapy did not reverse these effects, though it may slow age-related declines in reaction speed. Researchers say menopause could represent an important turning point for brain health.

For decades, Americans were surrounded by lead from car exhaust, factories, paint, and even drinking water, often without realizing the damage it caused. By analyzing hair samples preserved across generations, scientists uncovered a striking record of how exposure soared before environmental rules and then collapsed after leaded gasoline and other sources were phased out.

New research suggests that Epstein-Barr virus may actively provoke the immune system in people with multiple sclerosis. Scientists found large buildups of virus-targeting immune cells in the nervous systems of MS patients, far more than in their blood. One viral gene was active only in people with MS, hinting at a direct role in the disease. The findings could help guide new approaches to treatment.

Researchers have discovered a previously unknown enzyme that plays a crucial role in fat production. By blocking it, they stopped weight gain, reduced liver damage, and lowered harmful cholesterol levels in animal studies. The finding opens the door to a new kind of medication that could tackle obesity, fatty liver disease, and cardiovascular disease all at once.

Colorectal cancer has long baffled scientists because, unlike most tumors, patients often do better when their cancers are packed with immune-suppressing regulatory T cells. New research finally explains why. Scientists discovered that these T cells aren’t all the same: one subtype actually helps keep tumors in check, while another shields cancer from immune attack. The balance between these “good” and “bad” cells can determine whether a tumor grows or shrinks.

Scientists at Keck Medicine of USC are testing an experimental stem cell therapy that aims to restore the brain’s ability to produce dopamine, the chemical whose loss drives Parkinson’s disease. The early-stage clinical trial involves implanting lab-grown dopamine-producing cells directly into a key movement-control region of the brain, with the hope of slowing disease progression and improving motor function.

New research using rhesus monkeys suggests that the brain’s relationship with alcohol may begin forming long before a person ever takes a drink. Scientists found that exposure to alcohol before birth reshaped the brain’s dopamine system, a key player in motivation and reward, and those changes were linked to faster drinking later in adulthood.

Scientists in Australia have uncovered a clever new way to fight some of the most dangerous drug-resistant bacteria by targeting a sugar that exists only on bacterial cells. By designing antibodies that recognize this unique sugar, researchers were able to guide the immune system to attack and eliminate deadly infections that normally shrug off antibiotics.

A new imaging breakthrough combines ultrasound and light-based techniques to generate vivid 3D images that show both tissue structure and blood vessel activity. Developed by researchers at Caltech and USC, the system delivers detailed results quickly and without radiation or contrast dyes. It has already been used to image multiple parts of the human body. The approach could significantly improve cancer detection, nerve-damage monitoring, and brain imaging.

Researchers have figured out how psoriasis can quietly turn into joint disease for some patients. Immune cells formed in inflamed skin can travel through the blood and reach the joints, where they sometimes trigger inflammation. The key difference lies in the joint’s ability to keep those cells in check. This insight could help doctors identify warning signs early and prevent lasting joint damage.

People who switch to a fully unprocessed diet don’t just eat differently—they eat smarter. Research from the University of Bristol shows that when people avoid ultra-processed foods, they naturally pile their plates with fruits and vegetables, eating over 50% more food by weight while still consuming hundreds fewer calories each day. This happens because whole foods trigger a kind of built-in “nutritional intelligence,” nudging people toward nutrient-rich, lower-calorie options.

Kidney disease often creeps in silently, and many patients aren’t diagnosed until major damage is already done. New research shows that even “normal” kidney test results can signal danger if they’re unusually low for someone’s age. By mapping kidney function across the population, scientists revealed who’s quietly at higher risk. A new online tool could help doctors catch these warning signs years earlier.

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth. By testing every possible mutation in a critical hotspot, they found that some changes barely boost cancer signals, while others supercharge them. When matched against real patient data, the map accurately predicted cancer behavior across tissues.

Advanced care provided by air ambulance teams was linked to higher survival rates in major trauma patients. Researchers found that more people survived than predicted by standard models, including many with severe injuries and low chances of survival. Younger patients and those more responsive at first assessment benefited most. Outcomes for traumatic cardiac arrest also improved steadily over the study period.

At just two months old, babies are already organizing the world in their minds. Brain scans revealed distinct patterns as infants looked at pictures of animals, toys, and everyday objects, showing early category recognition. Scientists used AI to help decode these patterns, offering a rare glimpse into infant thinking. The results suggest babies begin learning and understanding far sooner than expected.

As bird flu continues to circulate in animals and spill over into humans, researchers are racing to stop it before it adapts to spread widely between people. A new nasal spray vaccine showed strong protection against H5N1 in animal tests, outperforming traditional flu shots. Because it targets the nose and lungs, it may prevent infection at the earliest stage.

Popular weight-loss drugs like Ozempic and Wegovy can dramatically curb appetite, but experts warn many users are flying blind when it comes to nutrition. New research suggests people taking these medications may not be getting enough guidance on protein, vitamins, and overall diet quality, increasing the risk of muscle loss and nutrient deficiencies.

A massive Swedish study tracking nearly 28,000 people for 25 years found an unexpected link between full-fat dairy and brain health. Among adults without a genetic risk for Alzheimer’s, eating more full-fat cheese was associated with a noticeably lower risk of developing the disease, while higher cream intake was tied to reduced dementia risk overall. The findings challenge decades of low-fat dietary advice but come with important caveats.

Scientists still don’t know how the brain turns physical activity into thoughts, feelings, and awareness—but a powerful new tool may help crack the mystery. Researchers at MIT are exploring transcranial focused ultrasound, a noninvasive technology that can precisely stimulate deep regions of the brain that were previously off-limits. In a new “roadmap” paper, they explain how this method could finally let scientists test cause-and-effect in consciousness research, not just observe correlations.

Scientists are digging into why heart disease risk in type 2 diabetes differs between men and women—and sex hormones may be part of the story. In a large Johns Hopkins study, men with higher testosterone had lower heart disease risk, while rising estradiol levels were linked to higher risk. These hormone effects were not seen in women. The results point toward more personalized approaches to heart disease prevention in diabetes.

Sound machines may not be the sleep saviors many believe. Researchers found that pink noise significantly reduced REM sleep, while simple earplugs did a better job protecting deep, restorative sleep from traffic noise. When pink noise was combined with outside noise, sleep quality dropped even further. The results suggest that popular “sleep sounds” could be doing more harm than good—particularly for kids.

Plants make chemical weapons to protect themselves, and many of these compounds have become vital to human medicine. Researchers found that one powerful plant chemical is produced using a gene that looks surprisingly bacterial. This suggests plants reuse microbial tools to invent new chemistry. The insight could help scientists discover new drugs and produce them more sustainably.